Calculate Exposure Impact from Feature-Exposure Correlation Networks

Generalized centrality-based exposure impact analysis using DEG, omics, or factor features.

Usage

run_exposure_impact(
  expomicset,
  feature_type = c("degs", "omics", "factor_features"),
  pval_col = "adj.P.Val",
  pval_thresh = 0.1,
  action = c("add", "get")
)

Arguments

expomicset

A MultiAssayExperiment object with correlation and network metadata.

feature_type

One of "degs", "omics", or "factor_features".

pval_col

Column in differential abundance results to filter DEGs. Default = "adj.P.Val".

pval_thresh

DEG p-value threshold. Ignored unless feature_type == "degs".

action

Either "add" (store in metadata) or "get" (return list).

Value

Either an updated MultiAssayExperiment (if action = "add") or a list.